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Laboratory of cellular and molecular immunology |
| Ministry of Education, Youth and Sports (Programme Johannes Amos Comenius): |
| INTER-MICRO: Talking microbes – understanding microbial interactions within One Health framework. (Investigator: Jan Jansa; institute of Microbiology of the CAS) Reg. No.: 0004597, 01.01.2024 - 30.06.2027 Work package 3 leader: Martin Schwarzer (Lab. 153) Research objective 1: Microbial murmurs: Microbial small talk over dinner (Martin Schwarzer, Lab. 153) Research objective 2: Barrier for bugs: Epithelial barrier as the means for communication (Jan Dobeš, Faculty of Science, Charles University) Research objective 3: Immunity to invaders: Dialogue with microbes for host resilience (Miloslav Kverka, Lab. 151) Research objective 4: Bellows from bowel: Gut microbiota calls to distant organs (Radka Roubalová, Lab. 151) Research objective 5: Songs from surroundings: Microbes as tools for communication between host and its environment (Jakub Kreisinger, Faculty of Science, Charles University) |
| Czech Science Foundation (GAČR): |
| 1)
Investigator: David Funda, MD., PhD. How does gluten-free diet prevent type 1 diabetes? (Co-investigator: Ondřej Štěpánek, PhD.; Institute of Molecular Genetics of the Czech Acad. Sci., Prague) Reg. No.: 22-21356S, 2022 - 2024 |
| 2)
Investigator: Klára Kostovčíková, PhD. Experimental ketogenic diet effect on immune response and ability of organism to cope with foreign substances (xenobiotics) in health and disease. (Co-investigator: assoc. prof. Eva Anzenbacherová, PhD.; Medical Faculty, Palacky University, Olomouc) Reg. No.: 23-05645S, 2023 - 2025 |
| Czech Health Research Council - Ministry of Health of the Czech Republic (AZV): |
| 1)
Co-investigator: Zuzana Jirásková Zakostelska, PhD. Microbiome, its role in effectiveness of immunomodulatory therapy and pathogenesis of MS. (Investigator: prof. Eva Kubala Havrdová, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU20-04-00077, 2020 - 2023 (extended) |
| 2) Investigator: Zuzana Jirásková Zakostelska, PhD. The role of microbiome in the development of atopic dermatitis and food allergy in infants and toddlers. (Co-investigator: Andrea Poloučková, MD.; Motol University Hospital, Prague) Reg. No.: NU20-05-00038, 2020 - 2023 (extended) |
| 3)
Co-investigator: Klára Kostovčíková, PhD.
The role of microbiome in pathogenesis of intraocular, systemic and central nervous system lymphoma. (Investigator: prof. Jarmila Heissigerová, MD. PhD.; First Faculty of Medicine, Charles Universit in Prague, Prague; Co-investigator: prof. Marek Trněný, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU20-03-00253, 2020 - 2023 (extended) |
| 4)
Co-investigator: Zuzana Jirásková Zakostelska, PhD. Dynamic parameters of glucose control in relation to biomarkers in serum and intraocular fluid in diabetic patients with ocular complications. (Investigator: prof. Martin Prázný, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU22-01-00077, 2022 - 2025 |
| 5)
Co-investigator: Klára Kostovčíková, PhD. Impact of microbiome on toxicity and efficacy of antitumor therapy of hematologic malignancies. (Investigator: prof. Marek Trněný, MD. PhD.; First Faculty of Medicine, Charles Universit in Prague, Prague; Co-investigator: Martin Špaček, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU22-03-00370, 2022 - 2025 |
| 6) Co-investigator: Zuzana Reiss, PhD. The effect of anti IL-17 therapy on skin and gut microbiota and intestinal barrier function in psoriasis patients. (Investigator: Filip Rob, MD., PhD.; Hospital Na Bulovce, Prague) Reg. No.: NU22J-05-00056, 2022 - 2025 |
| 7)
Co-investigator: Petra Procházková, PhD. The impact of gut microbiota on the onset and the course of anorexia nervosa in patients and in an experimental animal model. (Investigator: prof. Hana Papežová, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU22-04-00010, 2022 - 2025 |
| 8)
Co-investigator: David Funda, PhD. Nasal microbiome and molecular immune mechanisms in the prevention and pathogenesis of nasal polyps and chronic rhinitis; relation to olfactory disorders and allergies. (Co-investigator: prof. Jaromír Astl, MD. PhD.; Military University Hospital Prague, Prague) Reg. No.: NU22-04-00010, 2022 - 2025 |
| 9)
Co-investigator: Miloslav
Kverka, MD., PhD. Complex lifestyle modification in the treatment of non-alcoholic fatty liver disease. (Investigator: prof. Radan Brůha, MD. PhD.; Charles University, Prague; Co-investigator: Václav Šmíd, MD., PhD.; General University Hospital in Prague, Prague) Reg. No.: NU23-01-00288, 2023 - 2026 |
| 10)
Co-investigator: Radka Roubalová, PhD. Study on the effect of probiotics in the treatment of non-infectious uveitis. (Investigator: prof. Jarmila Heissigerová, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU23-05-00133, 2023 - 2026 |
| 11)
Co-investigator: Petra Procházková, PhD. The role of the gut microbiota in the autoimmune mechanisms of patients with psychogenic overeating and in the experimental model. (Investigator: prof. Hana Papežová, MD. PhD.; General University Hospital in Prague, Prague) Reg. No.: NU23-04-00381, 2023 - 2026 |
| Czech Academy of Sciences: |
| 1) Co-investigators: prof. Helena Tlaskalová-Hogenová, MD., DSc. Strategy AV21: Foods for the future. (Coordinator: prof. Jaroslav Doležel, DSc., Institute of Experimental Botany of theCzech Acad. Sci., Olomouc) Reg. No.: Research programme No. 19 |
| 2) Investigator: Miloslav
Kverka, MD., PhD. The effect of microbiota on inflammation and carcinogenesis. Reg. No.: Lumina quaeruntur LQ200202105, 2021 - 2025 |
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